Karen Canfell is the Director of the Daffodil Centre (a joint venture of Cancer Council NSW and The University of Sydney), Chair of Cancer Council Australia’s Cancer Screening and Immunisation Committee, and Adjunct Professor, University of Sydney. She leads a program of research which provides policy-makers with an evidence-base for decision making in cancer control. To date, a focus has been the interplay between HPV vaccination and cervical screening in both high and low resource countries. Her group regularly performs economic evaluations of new screening technologies for government agencies in Australia, New Zealand and England and she is a co-PI of an US NCI collaborative research grant, CISNET-Cervical, to evaluate new vaccination and screening options in the USA. Her team’s work underpins the recent transition of the National Cervical Screening Program in Australia to 5-yearly HPV-based screening.